Sizeİ: 15µm
Shape round
Nucleus round
Chromatin intermediate, very slightly condensed
Nucleolusİ: 1 clearly visible
Nuclear/Cytoplasmic Ratio (N/C)=0.6 with a lightly basophilic colour
Granulesİ: None

The prolymphocyte is seen pathologically in lymph node sections or on the blood and bone marrow films of patients with chronic lymphocytic leukaemia which is undergoing transformation towards a prolymphocytic leukaemia. In this situation the calculation of the percentage of prolymphocytes is crucial to the diagnosis.


It should be remembered that in these pathological areas an important feature is a hyperlymphocytosis, by definition greater than 4 x109/L.